haemorrhoids
Conditions
Interventions
Study Group:Local infiltration injection of 20ml bupivacaine liposome.
Control group:0.375% ropivacaine 20ml for local infiltration anaesthesia at the surgical incision.
Sponsors
Taikang Tongji (Wuhan) Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1) ASA classification I-III; 2) Patients diagnosed with grade III-IV internal or external haemorrhoids, or those with mixed haemorrhoids combined with prolapse; 3) BMI: 18-25 kg/m^2; 4) Age between 18-70 years; 5) Patients voluntarily participate in the trial and sign an informed consent form.
Exclusion criteria
Exclusion criteria: 1) A history of severe cardiovascular disease (heart function ?-?), abnormal coagulation function or use of anticoagulants or antiplatelet drugs that have not been discontinued pre-operatively, or liver, kidney dysfunction, or a history of mental illness; 2) Known allergy to local anaesthetics; 3) Localised infection at the site of operation or systemic infection; 4) Speech difficulties or communication issues; 5) Patient refusing to participate in the study or unwilling to undergo regional blockade; 6) Patients with coexisting sensory disorders like pain hypersensitivity, or other somatic pain affecting postoperative pain assessment; 7) A history of chronic opioid use (over three months or morphine equivalent exceeding 5mg/day for a month); 8) Patients deemed by the investigator to have any other factors making them unsuitable for participation in this trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Time to first postoperative compression of the analgesic pump;Opioid consumption within 72 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| NRS pain score within 72 hours postoperatively;Time to first get out of bed;Adverse effects;Satisfaction; | — |
Countries
China
Contacts
Public ContactHuang Junjie
Taikang Tongji (Wuhan) Hospital
Outcome results
None listed