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Through-the-scope twin clip closure of large gastric defects after full-thickness resection: a prospective multicenter randomized controlled trial

Through-the-scope twin clip closure of large gastric defects after full-thickness resection: a prospective multicenter randomized controlled trial

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100392
Enrollment
Unknown
Registered
2025-04-08
Start date
2025-04-25
Completion date
Unknown
Last updated
2025-06-24

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Gastric submucosal tumors

Interventions

Sponsors

Chinese PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1.Gastric SMTs (1-5 cm); 2.Preoperative confirmation of tumor origin from the muscularis propria layer by endoscopic ultrasound (EUS); 3.Age range 18-80 years; 4.Willingness to participate with signed written informed consent.

Exclusion criteria

Exclusion criteria: 1.Gastric submucosal tumors (SMTs) originating from the muscularis mucosae or submucosal layer; 2.Preoperatively assessed SMTs with high suspicion of malignancy, confirmed malignant transformation, or metastasis; 3.SMTs predominantly exhibiting extraluminal growth toward the serosal layer, with poor endoscopic intraluminal visualization; 4.Patients with severe cardiopulmonary comorbidities, coagulation dysfunction, or contraindications to surgical/anesthetic procedures; 5.Postoperative cases with partial injury to the muscularis propria layer, excluding full-thickness defects; 6.Patients who declined participation or refused to provide written informed consent; 7.Other conditions deemed ineligible by endoscopic evaluation or clinician judgment.

Design outcomes

Primary

MeasureTime frame
Closure time;

Secondary

MeasureTime frame
Closure efficiency;Complete closure success rate;Number of metal clips ;

Countries

China

Contacts

Public ContactZhai Yaqi

Chinese PLA General Hospital

astaring@163.com+86 138 1010 5934

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026