Advanced Angle-Closure Glaucoma
Conditions
Interventions
Lens Extraction Combined with Goniosynechialysis Group:NA
Lens Extraction Combined with Goniosynechialysis and Goniotomy Group:NA
Sponsors
EYE & ENT Hospital of Fudan University
Eligibility
Sex/Gender
All
Age
45 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1. Age between 45 and 75 years; 2. Gonioscopic examination showing synechial angle closure exceeding 180 degrees; 3. Use of two or more types of medication; 4. Intraocular pressure higher than 21 mmHg; 5. Mean deviation (MD) worse than 12 dB on Octopus visual field testing.
Exclusion criteria
Exclusion criteria: 1. Snellen visual acuity worse than hand motion; 2. History of ocular trauma; 3. History of intraocular surgery; 4. History of uveitis; 5. Severe conjunctival scarring; 6. Iris or angle neovascularization; 7. Aphakia or pseudophakia (absence of natural lens or presence of an intraocular lens); 8. Corneal endothelial cell count < 1200 cells/mm²; 9. Other severe ocular conditions that significantly affect visual function, such as wet macular degeneration or high myopia.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| intraocular pressure, IOP; | — |
Secondary
| Measure | Time frame |
|---|---|
| Best corrected visual acuity, BCVA;diopter;visual field;Glaucoma Optical Coherence Tomography;number of topical medications used; | — |
Countries
China
Contacts
Public ContactYuhong Chen
EYE & ENT Hospital of Fudan University
Outcome results
None listed