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Efficacy and safety of different methods and doses for thirst management in patients with MV-OTI and NPO: A Randomized, Controlled Three-Arm Trial

Efficacy and safety of different methods and doses for thirst management in patients with MV-OTI and NPO: A Randomized, Controlled Three-Arm Trial

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100368
Enrollment
Unknown
Registered
2025-04-08
Start date
2022-01-14
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Mechanical ventilation and drinking and fasting

Interventions

Group A: 1.6ml room-temperature water (20-25?) injection:Room-temperature drinking water (20-25?), 1.6 ml, administered via a needleless syringe. Healthcare personnel inject the water between the mola
Group B: 1.6ml cold water (2-6?) spray:Water temperature and dosage: Chilled drinking water (2-6?) with a total volume of 1.6 ml. Measurement tool: A spray bottle delivering 0.1 ml per spray, with a
Group C: 5ml cold water (2-6?) spray:In Group C, the water temperature and dosage are chilled water at 2-6? with a total volume of 5 ml. The measurement tool is a spray bottle delivering 0.1 ml per s

Sponsors

Affiliated Hospital of Zunyi Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age >= 18 years; 2.Patient is conscious, or has a Richmond Agitation-Sedation Scale (RASS) score between -1 and 1, with normal swallowing function; 3.Oral endotracheal intubation and fasting during the study period; 4.Initial Numeric Rating Scale (NRS) score for thirst >= 3; 5. Patient is able to understand and correctly respond to instructions from healthcare personnel; 6.Voluntary participation and signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with oral infections, oral diseases, or Sjögren's syndrome; 2.Patients receiving enteral nutrition or who have had their endotracheal tube removed during the study; 3.Patients or family members requesting to withdraw from the study; 4.Patients unable to participate due to medical conditions, as assessed by the attending physician; 5.Patients transferred, discharged, or deceased during the study.

Design outcomes

Primary

MeasureTime frame
Visual Thirst intensity Scale, V-TIS;

Secondary

MeasureTime frame
Visual Thirst Distress( Discomfort )Scale, V-TDS;Visual of Sleep quality Scale,V-SQS;Oral mucosa wetness scale ,OMWS;Number of additional interventions,NAI;

Countries

China

Contacts

Public ContactYou Yuan

Affiliated Hospital of Zunyi Medical University

377426686@qq.com+86 187 9812 0470

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026