Type 2 Diabetes Mellitus
Conditions
Interventions
Observation group:N/A
Sponsors
The Fifth-Affiliated Hospital of Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
40 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Diagnosed as type 2 diabetes mellitus according to the diagnostic criteria in the Chinese Guidelines for the Prevention and Treatment of Type 2 Diabetes (2020 edition); 2.Age >40 and <= 80 years, any gender; 3.Patients who completed QCT and DXA bone density examinations during hospitalization and completed a standardized questionnaire (including lifestyle, past diseases, history of smoking and drinking, history of medication such as adrenal cortex hormones, and risk factors in FRAX fracture risk assessment); 4.Have complete clinical information and body measurement data; 5.Normal mental and cognitive status, not long-term bedridden patients.
Exclusion criteria
Exclusion criteria: 1.Other types of diabetes; 2.Presence of diseases that affect bone metabolism, such as thyroid dysfunction, parathyroid disease, bone tumors, rheumatoid arthritis, ankylosing spondylitis, systemic lupus erythematosus, Cushing's syndrome, metabolic bone disease and other endocrine diseases, severe liver and kidney dysfunction, inflammatory bowel disease and other nutritional dysfunctions, etc; 3.Long-term use of drugs that affect bone metabolism, such as glucocorticoids; 4.Those with incomplete information collection.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The mean bone density (mg/cc) of lumbar spine Quantitative omputed Tomography (QCT) ?;The T/Z scores of Dual-Energy X-ray Absorptiometry (DXA).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Bone trabecular score;FRAX fracture risk tool 10-year probability of major osteoporotic fracture (%) and 10-year probability of hip fracture (%);Waist-to-hip ratio;Body mass index;VisceralAdiposityIndex;Triglyceride-Glucose Index; | — |
Countries
China
Contacts
Public ContactYingjuan Zeng
The Fifth-Affiliated Hospital of Sun Yat-sen University
Outcome results
None listed