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Application of different sedatives combined with afentanil in painless hysteroscopy

Application of different sedatives combined with afentanil in painless hysteroscopy

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100358
Enrollment
Unknown
Registered
2025-04-08
Start date
2023-10-31
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Hysteroscopy

Interventions

Control group A:Receiving alfentanil combined with propofol anesthesia
Experimental group B:Received anesthesia with alfentanil combined with ciprofloxacin
Experimental group C:Received anesthesia with alfentanil combined with remazolam benzenesulfonate

Sponsors

Gansu Provincial Hospital
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Voluntarily sign the informed consent form for this study; 2. Stable vital signs, aged between 18 and 60 years; 3. Hysteroscopy or treatment for various reasons; 4. ASA Grades I–II; 5. No allergy to anesthetic drugs, and no contraindications to anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with difficult airway, modified Mallampati score of grade III or IV; 2. Patients with respiratory or cardiac dysfunction; 3. Abnormal blood routine or blood biochemical examination before hysteroscopy, suffering from severe neuropsychiatric diseases; 4. Patients who have used benzodiazepines or opioids intermittently in the past 1 month or the past 3 months; 5. Patients with allergies or contraindications to benzodiazepines, opioids, propofol, flumazenil or naloxone; 6. Unaccompanied or guardian; 7. Patients with abnormal hearing and vision, unable to communicate normally; 8. Patients who are unable to provide or refuse to sign the informed consent form.

Design outcomes

Primary

MeasureTime frame
Incidence of intraoperative hypoxemia;

Secondary

MeasureTime frame
Patient and anesthesiologist satisfaction;Incidence of other adverse reactions;Intraoperative mean arterial pressure, heart rate and oxygen saturation;Intraoperative operation time, awakening time and time out of the room;

Countries

China

Contacts

Public ContactWang Dong

Gansu Provincial People's Hospital

736922854@qq.com+86 138 9327 2607

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026