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Efficacy and safety of the cold and hot modes of snare polypectomy for colorectal multiple adenomas in familial adenomatous polyposis: a single-center, randomized, controlled study

Efficacy and safety of the cold and hot modes of snare polypectomy for colorectal multiple adenomas in familial adenomatous polyposis

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100353
Enrollment
Unknown
Registered
2025-04-08
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Familial adenomatous polyposis

Interventions

cold snare polypectomy group:Direct mechanical strangulation using a cold ferrule.
hot snare polypectomy group:Strangulation using a high-frequency electrocoagulation coiler

Sponsors

Department of Gastroenterology, No. 900 Hospital of the Joint Logistics Force of the People's Liberation Army, China
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: 1. Patients with FAP who have an intact colon or have undergone partial colectomy; 2.The number of adenomas >=10 mm in diameter in the colon is 15 or more.

Exclusion criteria

Exclusion criteria: 1. Endoscopic diagnosis of deep invasive submucosal carcinoma; 2. Bleeding tendency, using anticoagulants; 3. Those with coagulation disorders; 4. Those with severe cardiac, hepatic or renal insufficiency; 5. Inadequate bowel preparation (Boston score <6).

Design outcomes

Primary

MeasureTime frame
Histologically complete resection rate;Whole-mount resection rate;

Secondary

MeasureTime frame
Intraoperative bleeding;Delayed postoperative bleeding;electrocoagulation syndrome (ECS);perforate;abdominal pain;Endoscopic treatment time;Post-operative recovery time;Health economics analysis;

Countries

China

Contacts

Public ContactZhou Linxin

Chinese People's Liberation Army Joint Logistics Force 900th Hospital

971152478@qq.com+86 139 5935 0848

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026