Nasopharyngeal carcinoma
Conditions
Interventions
Gold Standard:Nasopharyngeal biopsy or nasopharyngeal endoscopy
Index test:Epstein-Barr virus antibody combined with Epstein-Barr virus Cp methylation detection for the nasopharyngeal carcinoma diagnosis
Sponsors
Sun Yat-sen University Cancer Center
Eligibility
Sex/Gender
All
Age
30 Years to 69 Years
Inclusion criteria
Inclusion criteria: 1) Registered residents aged 30-69 in the screening area; 2) No history of nasopharyngeal cancer; 3) ECOG 0-2; 4) The participant agrees to sign the informed consent.
Exclusion criteria
Exclusion criteria: 1) Patients with heart, brain, liver, lung and kidney diseases; 2) Patients with autoimmune diseases; 3) Patients currently receiving glucocorticoid or immunosuppressive therapy; 4) People with poor mental state, unclear consciousness.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Sensitivity of preliminary screening indicators for nasopharyngeal carcinoma;Specificity of preliminary screening indicators for nasopharyngeal carcinoma;Accuracy; | — |
Secondary
| Measure | Time frame |
|---|---|
| Positive prediction value of biological preliminary screening indicators for nasopharyngeal carcinoma;Sensitivity of E-CpMQ combined with MRI for diagnostic screening; | — |
Countries
China
Contacts
Public ContactCao Sumei
Sun Yat-sen University Cancer Center
Outcome results
None listed