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Research on the Efficacy and Mechanism of Light Therapy in Improving Cognitive Executive Function in Depression

Research on the Efficacy and Mechanism of Light Therapy in Improving Cognitive Executive Function in Depression

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100327
Enrollment
Unknown
Registered
2025-04-08
Start date
2025-04-10
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Depression

Interventions

Experimental group:Light therapy is used, with a treatment time of 30 minutes and a treatment intensity of 10000 lux, once a day for 2 weeks, 5 times a week, for a total of 10 sessions.
Blank group:NONE
Control group:The treatment time is 30 minutes using light pseudo stimulation, with a treatment intensity of 200lux, once a day for 2 weeks, 5 times a week, for a total of 10 sessions.

Sponsors

Affiliated Kangning Hospital of Ningbo University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 80 Years

Inclusion criteria

Inclusion criteria: 1. Age: 18-80 years old; 2. Patients diagnosed with "depressive attack" according to the International Classification of Diseases (ICD-10); 3. The total baseline score of Hamilton Depression Scale (HDMD) is greater than 7 points; 4. The total score of the cognitive function defect self-evaluation scale (PDQ-D) is greater than 10 points; 5. Sign informed consent form.

Exclusion criteria

Exclusion criteria: 1. Patients suffering from other mental illnesses (such as schizophrenia, substance abuse, etc.); 2. Patients suffering from severe organic diseases (such as those with severe liver and renal dysfunction and brain organic diseases); 3. Patients with contraindications in light treatment (ophthalmic diseases glaucoma, cataracts, etc., dermatological diseases systemic lupus erythematosus, solar dermatitis, etc.); 4. Patients who have participated in physical therapy in the past month; 5. Patients who refused to participate in this study.

Design outcomes

Primary

MeasureTime frame
Perceived Deficits Questionnaire Depression, PDQ-D;Chinese Brief Cognitive Battery Test, CBCT;Brain-derived neurotrophic factors;Functional Near-infrared Spectroscopy;

Secondary

MeasureTime frame
Pittsburgh sleep quality index, PSQI;Insomnia Severity Index, ISI;Hamilton Depression Scale, HAMD;

Countries

China

Contacts

Public ContactYongming Xu

Affiliated Kangning Hospital of Ningbo University

171664348@qq.com+86 574 26302634

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026