postoperative nausea and vomiting
Conditions
Interventions
Group R:Anesthesia with remimazolam
Sponsors
The First Affiliated Hospital of Soochow University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. American Society of Anesthesiologists (ASA) physical status I to III; 2. 18 years old <= Age <= 65 years old; 3.Patients scheduled for thyroid surgery under general anesthesia.
Exclusion criteria
Exclusion criteria: 1. Hyperthyroidism or hypothyroidism; 2. History of central nervous system disease, psychiatric disease or speech communication disorder; 3. myocardial infarction within 6 months before screening, resting ECG heart rate 30kg/m^2; 5. Renal replacement therapy required or Child Pugh C grade; 6. Patients with severe respiratory tract pathologies (obstructive sleep apnea syndrome, mouth opening disorder, limited neck or jaw movement,tracheal compression, etc.); 7. Long-term history of sedative, antidepressant or psychoactive drug abuse, history of alcoholism, etc; 8. Pregnancy or lactation; 9. Allergy to any drug used in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| incidence of post-operative nausea and vomiting; | — |
Secondary
| Measure | Time frame |
|---|---|
| the severity of PONV;nausea;vomiting;antiemetic rescue therapy;Quality of postoperative recovery;Postoperative sleep quality;The time of disappearance of consciousness and body movement after induction of general anesthesia;Hemodynamic changes;Incidence of postoperative delirium;Patient comfort satisfaction score; | — |
Countries
China
Contacts
Public ContactCheng Hao
The First Affiliated Hospital of Soochow University
Outcome results
None listed