Postoperative delirium (POD) is an acute syndrome of the central nervous system, presenting with attention disorders, disordered consciousness levels, cognitive impairments, sleep-wake cycle disorders, abnormal neurological movements and emotional instability. Postoperative neurocognitive impairment (POCD) includes new-onset neurocognitive impairments within 30 days after discharge from hospital a
Conditions
Interventions
Malnutrition cohort:None
Normal nutrition cohort:None
Sponsors
Suining Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. The selected patients should be aged 18 years or above. 2. The length of hospital stay should be no less than 7 days. 3. The duration of general anesthesia should be no less than 2 hour. 4. Primary school education level or above; 5. There should be no severe neurological disorders. 6. The patients should possess the ability to read, understand spoken language and cooperate with neuropsychological tests
Exclusion criteria
Exclusion criteria: 1. Cancer patients 2. Patients with cognitive impairment diagnosed as dementia by MMSE: (1) Cancer patients (2) Patients with MMSE score <= 23 before surgery (3) Difficulties in cognitive function assessment (patients with low compliance, hearing, vision, reading and comprehension impairments) (4) Had experienced cardiovascular and cerebrovascular accide scale before surgery 3. Difficulties in assessing cognitive function (patients with low compliance, hearing, vision, reading and comprehension impairments) 4. Had suffered from cardiovascular and cerebrovascular accidents within the past 6 months 5. Underwent secondary surgery or other surgeries during the current hospitalization 6. Had been diagnosed with any neurological disease in the past (Alzheimer's disease, Parkinson's disease, etc.) 7. Had a history of cerebral infarction or cerebral ischemia in the past.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative delirium;Postoperative cognitive dysfunction; | — |
Countries
China
Contacts
Public ContactLuoLi
Suining Central Hospital
Outcome results
None listed