Anterior cruciate ligament reconstruction
Conditions
Interventions
Phase I of the study (observational study): ALR patient group:None
Phase I of the study (observational study): Healthy control group:None
Phase II of the study (observational study): Longitudinal observation group:None
Phase III of the study (interventional study): experimental group:Receive real tDCS stimulation for 15 minutes twice a week
Phase III of the study (interventional study): control group:Receive sham tDCS (i.e., electrical stimulation only 30 sec after start, stop thereafter)
Sponsors
Shanghai University of Sport Yangpu campus
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: Phase 1 & 2 of the study: Study 1: Patient Inclusion Criteria: 1. Age 18-40 years; 2. Body mass index (BMI) =5; 4. The right leg is the dominant leg; 5. After ACL reconstruction, patients need to undergo ACL reconstruction surgery for the first time with left autologous hamstring tendon; 6. Receive standard rehabilitation after ACL reconstruction. Healthy control group: no history of lower limb surgery or injury in the past 6 months, and the patients were matched one-to-one by gender, age, dominant leg, exercise program, and exercise level. All subjects in this study were required to meet the requirements of fMRI and TMS testing, including: 1. no metal implants in the head and neck, 2. no neurological diseases, such as epilepsy, severe migraine, and concussion within the past 6 months. Study II: ACL Reconstructed Athletes Inclusion Criteria are as follows: 1. Age 18-35 years; 2. Engaged in competitive sports before injury (Tegner sports level score of 7 or above); 3. Received unilateral reconstructive surgery for ACL for the first time for 6 months or more; 4. Meet RTS clinical criteria (quadriceps strength symmetry >=85%, one-legged jump length symmetry >=85%). In this study, a control group of healthy athletes will be constructed by matching them one-to-one with ACL reconstructed athletes by gender, age, athletic program, exercise level. Phase 3 of the study: The inclusion criteria for patients are as follows: 1. Age 18-40 years old; 2. Body mass index (BMI) =5; 4. Received unilateral autologous hamstring tendon ACL reconstruction surgery for the first time; 5. Receive standard rehabilitation treatment after ACL reconstruction.
Exclusion criteria
Exclusion criteria: Phase 1 & 2 of the study: 1. Other surgeries on both lower limbs; 2. Other injuries in both lower limbs in the past 6 months; 3. Have any chronic cardiovascular and metabolic diseases, or be pregnant; 4. Underwent multiple ligament reconstruction; 5. Patients who have undergone meniscus repair, removal, or articular cartilage surgery are unable to receive standard postoperative rehabilitation. Phase 3 of the study: 1. Other surgeries on both lower limbs; 2. Other injuries in both lower limbs in the past 6 months; 3. Have any chronic cardiovascular and metabolic diseases, or be pregnant; 4. Underwent multiple ligament reconstruction; 5. Patients who have undergone meniscus repair, removal, or articular cartilage surgery and are unable to receive standard postoperative rehabilitation treatment; 6. Metal implants in the head and neck.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| All areas of the cerebral cortex are BOLD;QuadricepRMT;QuadricepMEP;QuadricepSICI;QuadricepLICF;Biomechanical index of jump;CAR;MVIC; | — |
Countries
China
Contacts
Public ContactQiu Jihong
Shanghai Sport University Yangpu Campus
Outcome results
None listed