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Clinical significance of neutrophil extracellular trap net and Gasdermin D in sepsis-associated coagulation disorders

Clinical significance of neutrophil extracellular trap net and Gasdermin D in sepsis-associated coagulation disorders

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100284
Enrollment
Unknown
Registered
2025-04-07
Start date
2023-10-09
Completion date
Unknown
Last updated
2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Sepsis

Interventions

Sepsis with SIC:None
Sepsis without SIC:None

Sponsors

Yantai Yuhuangding Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1.Age > 18 years; 2.Length of stay in the Intensive Care Unit (ICU) > 24 hours; 3.Diagnosis of sepsis (defined as a clinical suspicion of infection with a Sequential Organ Failure Assessment (SOFA) score > 2, consistent with the Sepsis-3 definition).

Exclusion criteria

Exclusion criteria: Have underlying liver and hematologic diseases.

Design outcomes

Primary

MeasureTime frame
N-GSDMD;MPO-DNA;—

Secondary

MeasureTime frame
MMP-9;syndecan-1;—

Countries

China

Contacts

Public ContactShan Xiaoxi

Yantai Yuhuangding Hospital

shanxiaoxi2006@126.com+86 137 9255 7530

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026