Bronchial asthma,rhinitis,
Conditions
Interventions
Healthy control group:None
Non-desensitization treatment group:None
Desensitization treatment group:None
Sponsors
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Eligibility
Sex/Gender
All
Age
5 Years to No maximum
Inclusion criteria
Inclusion criteria: 1.Age >=5 years old, meet the diagnostic criteria of bronchial asthma, allergic rhinitis, etc. 2.The detection of relevant allergens met the criteria for mite allergen specific immunotherapy. 3.Patients who had received subcutaneous mite allergen immunotherapy (SCIT) for 1 year or less or were about to start SCIT. 4.About 200 patients with respiratory allergic diseases without desensitization treatment and the same number of healthy children were followed up.
Exclusion criteria
Exclusion criteria: 1. Any child presenting with mental retardation; 2.Children with psychiatric or neurological disorders such as anxiety, depression, epilepsy; 3.Children with severe cardiovascular disease; 4.Children with primary or secondary immunodeficiency; 5.Children whose family members could not obtain informed consent or withdrew from the program; 6.Any other conditions considered by the investigator to be ineligible for inclusion in the study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Improvement in SNAP-IV-18; | — |
Secondary
| Measure | Time frame |
|---|---|
| Rhinitis (AR) symptom score;Asthma symptom score;RCAT controls the score;Asthma quality of life;DSM-IV Diagnostic Scale Score;ACT control score;CONNERS parents use questionnaires score;Rhinitis quality of life;PSQI; | — |
Countries
China
Contacts
Public ContactDing Bo
Renji Hospital affiliated to Shanghai Jiaotong University School of Medicine
Outcome results
None listed