Acute Ischemic Stroke
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients who met the indications for intravenous thrombolysis or mechanical thrombectomy in acute ischemic stroke, had no contraindications, and underwent mechanical thrombectomy; 2.Patients showing non-symptomatic intracranial hemorrhage (Heidelberg Bleeding Classification Grade 1) on head CT within 24 hours post-procedure; 3.Patients with stable vital signs (resting heart rate 50-100 bpm; systolic blood pressure 100-160 mmHg; SpO2 >=90%) and a Glasgow Coma Scale (GCS) score >=9.
Exclusion criteria
Exclusion criteria: 1.re-stroke modified Rankin Scale (mRS) score >=2; 2.Severe dysfunction of major organs (heart, liver, kidneys, etc.) or concurrent serious neurological disorders (e.g., brain tumors); 3.Patients unable to cooperate with rehabilitation training and assessment (e.g., those with severe cognitive impairment or mental disorders); 4.Patients or their legal representatives declining participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Modified Rankin Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| Modified Barthel Index;National Institutes of Health Stroke Scale;Fugl-Meyer Assessment ;Interleukin-6;Interleukin-10;Neutrophil-to-Lymphocyte Ratio;Matrix Metalloproteinase-9;Soluble Suppression of Tumorigenicity 2; | — |
Countries
China
Contacts
Tangshan People's Hospital; Tianjin Medical University General Hospital