The effect of sequential cardiac rehabilitation program combined with external counterpulsation and exercise on patients with coronary heart disease: a randomized controlled non inferiority trial

Study on the intervention effect of sequential cardiac rehabilitation program combined with external counterpulsation and exercise on patients with coronary heart disease: a randomized controlled non-inferiority trial

Status

Active, not recruiting

Phases

Phase 3

Study type

Interventional

Source

ChiCTR

Registry ID

ChiCTR2500100218

Enrollment

Unknown

Registered

2025-04-06

Start date

2025-04-07

Completion date

Unknown

Last updated

2025-04-14

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Coronary artery disease

Interventions

Exercise-based cardiac rehabilitation program group:Exercise-based cardiac rehabilitation program

Sequential cardiac rehabilitation program group based on external counterpulsation combined with exercise group:Sequential cardiac rehabilitation program group based on external counterpulsation combi

Eligibility

Sex/Gender

All

Age

30 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. Suffering from coronary heart disease: percutaneous coronary angiography and coronary CT angiography show a single vessel stenosis degree of 50% or a positive exercise stress test; 2. Age range of 30-75 years old (including threshold), gender not limited; 3. The exercise risk stratification for coronary heart disease is classified as medium to low risk; 4. Educational level of primary school education or above, able to understand various questionnaires; 5. Informed consent and voluntary participation in this study.

Exclusion criteria

Exclusion criteria: 1. Suffering from severe mental illness; 2. Suffering from other serious illnesses (severe pneumonia, cerebral hemorrhage or subarachnoid hemorrhage, severe liver and kidney dysfunction, etc.); 3. There are implantable devices (pacemakers or ICD, CRT); 4. Decompensated or acute heart failure; 5. Severe arrhythmia (ventricular tachycardia, ventricular flutter and fibrillation, supraventricular tachycardia, rapid atrial fibrillation, severe bradycardia (<50 beats/minute in a quiet state), second degree or higher atrioventricular block); 6. Severe diseases that restrict exercise testing and training (such as lumbar spinal stenosis and severe degenerative knee arthritis); 7. Suffering from diseases that lead to a life expectancy of less than one year (such as malignant tumors).

Design outcomes

Primary

Measure	Time frame
Peak oxygen uptake;	—

Secondary

Measure	Time frame
Mental health status;Physical fitness;Quality of life;Cardiac rehabilitation adherence;Incidence rate of safety incidents;	—

Countries

China

Contacts

Public ContactXun Gong

Hunan Provincial People's Hospital

hunanheart@163.com+86 156 1613 5101

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026