Vomiting and acute and chronic pain after thoracoscopic lobectomy
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: Collected from April 2025 ~ September 2026 The Second Affiliated Hospital of Fujian Medical University plans to undergo elective thoracoscopic lobectomy, ASA (American Society of Anesthesiologists) is graded as I~II, age 18~70 years old, normal communication, full understanding of the purpose and significance of this study, and willing to participate in this study Lung adenocarcinoma patients, the hospital ethics committee passed, signed the informed consent.
Exclusion criteria
Exclusion criteria: 1. Allergic to local anesthetics; 2. Patients with Intraoperative freeze pathology ruled out lung adenocarcinoma or other lung diseases found during the operation; 3. Postoperative chemotherapy with neurotoxicity; 4. History of repeated operations; 5. Any medical condition that occurs during the study period that may put participant at risk for continuing the study; 6. Participants who could not complete the trial according to the provisions of the trial protocol (nerve block failure, follow-up failure, etc.).
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Postoperative nausea and vomiting score;Postoperative VAS score;Incidence of postoperative chronic pain;Postoperative sleep quality score;P substance;Serotonin;ß-endorphins;Postoperative antiemetic drug dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Sufentanil dosage;Remifentanil dosage;Number of effective compressions of the analgesic pump;Postoperative analgesics dosage;Vasoactive drug dosage;Operation time;Recovery time; | — |
Countries
China
Contacts
The Second Affiliated Hospital of Fujian Medical University