Autism
Conditions
Interventions
Viable bacteria preparation intervention group:Oral probiotic preparation treatment with high production of 5-HTP: direct oral administration or warm boiled water and other preparations daily, dosage
Take it continuously for 6 months. Antimicrobials need to be discontinued or cross-used during the course of the treatment study.
Placebo group:Placebo is taken directly orally or with warm water every day, with a dosage of 1 bag (2g)/time, 2 times/d
Sponsors
Maternal and Child Health Hospital of Hubei Province
Eligibility
Sex/Gender
All
Age
3 Years to 8 Years
Inclusion criteria
Inclusion criteria: 1. Patient age: 3-8 years old. 2. Patients diagnosed with childhood autism using international standards, and have not used antibiotics or antibiotic drugs within two weeks before treatment, have no severe diarrhea, and have a regular diet. 3. Special comprehensive intervention treatment for children with autism is planned.
Exclusion criteria
Exclusion criteria: 1. Failure to carry out special comprehensive intervention treatment for children with autism; 2. The final diagnosis was not childhood autism; 3. Other conditions (e.g., severe food allergies, etc.) that are not suitable for intervention by the physician.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Metabolomics differences;Metagenomic differences; | — |
Countries
China
Contacts
Public ContactZiming Huang, Hong Wang
Maternal and Child Health Hospital of Hubei Province
Outcome results
None listed