ACS patients with non-criminal vulnerable plaque characteristics
Conditions
Interventions
Experimental group:Drug-eluting balloon + standard drug therapy group
Control group:Standard drug treatment group
Sponsors
The Second Affiliated Hospital of Harbin Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: (1) Subject 18 years old 0.8; (5) Non-criminal plaques meet any two requirements of IVUS-PB>65%, OCT-MLA180°; (6) Agree to join the group and sign a written informed consent.
Exclusion criteria
Exclusion criteria: (1) Patients who are allergic to aspirin, clopidogrel, ticagrelor, heparin, contrast agent and paclitaxel, patients with systemic lupus erythematosus or other systemic immune diseases; (2) hypotension, shock, or the need for mechanical support or intravenous vasopressors; (3) Patients with a history of severe renal insufficiency; (4) Pregnant or lactating women; (5) Subjects with EF 30%; (3) The target lesions were bifurcated lesions, with branch vessel diameter >2mm and stenosis >50%. (4) The angiography showed serious calcification or tortuosity of the vessel where the target lesion was located; (5) Lesions involving the opening of the LAD, LCX, or RCA (within 3mm of the opening); (6) The target lesions were located in the pontine vessels.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| OCT/IVUS/OCT-IVS;MACE; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood routine examination;blood biochemistry;Markers of myocardial injury;BNP/NT-proBNP;glycosylated hemoglobin;ECG;ultrasonic cardiogram;CAG; | — |
Countries
China
Contacts
Public ContactBo Yu
The Second Affiliated Hospital of Harbin Medical University
Outcome results
None listed