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Randomized controlled trial of acupuncture in the treatment of knee osteoarthritis and its metabolic mechanism

Randomized controlled trial of acupuncture in the treatment of knee osteoarthritis and its metabolic mechanism

Status
Active, not recruiting
Phases
Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100182
Enrollment
Unknown
Registered
2025-04-03
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

knee osteoarthritis

Interventions

acupuncture group:The Inner Knee Eye, Sea of Blood, Liangqiu, Yanglingquan, Da Loom, Taichong, and Ah Yes points were selected. Acupuncture treatment was performed 3 times a week for 8 weeks, for a to
sham acupuncture group :Non-meridian and non-acupuncture points were selected for shallow stabbing with a depth of about 2 mm, without manipulation, without seeking to obtain qi, and the non-acupunctu

Sponsors

Chengdu Bayi Orthopedics hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
45 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1. Meet the diagnostic criteria for knee osteoarthritis (KOA) formulated by the American College of Rheumatology (ACR): (1) Age>=40 years and =6 months; (3) X-ray examination (Kellgren-Lawrence classification) is grade II-III. 2. Visual analogue score (VAS) > = 4 points and < = 7 points (moderate pain level). 3. Have not received other acupuncture, massage or intra-articular injection treatment in the past 1 month. 4. Voluntarily sign the informed consent form and promise to complete the full course of treatment and follow-up.

Exclusion criteria

Exclusion criteria: 1. Secondary knee osteoarthritis (such as rheumatoid arthritis, traumatic arthritis, gouty arthritis, etc.). 2. Combined with severe cardiovascular and cerebrovascular diseases (such as NYHA cardiac function classification >=grade III), liver and kidney insufficiency (ALT/AST>=2 times the upper limit of normal value, Cr>=1.5 mg/dL) or malignant tumor. 3. Those who have a history of knee surgery or plan to undergo surgery within 6 months. 4. Pregnant or lactating women. 5. Coagulation dysfunction (INR>=1.5 or platelet count =5 mg/d prednisone equivalent) or immunosuppressants. 8. Those with mental illness or cognitive impairment who cannot cooperate with treatment. 9. Those who participate in other clinical trials that may interfere with the results of this study.

Design outcomes

Primary

MeasureTime frame
Osteoarthritis index;Musculoskeletal ultrasound analysis metrics;

Secondary

MeasureTime frame
Osteoarthritis index;

Countries

China

Contacts

Public ContactTianming Man

Chengdu Bayi Orthopedics hospital

1368163630@qq.com+86 186 0466 3520

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026