Pain on propofol injection
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. Patients aged from 18 to 60 years old; 2. Routine acceptance of upper gastrointestinal endoscopy; 3. ASA grade: Grade I or Grade II; 4. Body mass index is greater than 18 kg/m^2 and less than 28 kg / m^2 (obesity); 5. The intravenous injection site is the back of the hand or the forearm (the size and site of the indwelling needle) 6. Voluntary signing of the informed consent form for anesthesia.
Exclusion criteria
Exclusion criteria: 1. Patients with a contraindication for conventional endoscopic procedures or for refusing anesthesia. 2. Life-threatening circulation, respiratory diseases, active massive bleeding with shock, etc., where the condition is not properly controlled. 3. Liver dysfunction (Child-Pugh C or above), gastrointestinal obstruction, cold fever, bronchial asthma, severe neurological diseases in the past month, etc. 4. Anxiety / depression; 5. Having a history of drug use or such alcohol abuse; 6. The evaluation of patients with a clear difficult airway, patients with morbid obesity and confirmed obstructive sleep apnea can not complete the painless gastroscopy in the outpatient clinic. 7. Unaccompanied people. 8. Patients with allergy or contraindications to propofol; 9. Pregnant women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Pain on propofol injection;Total dose of propofol; | — |
Secondary
| Measure | Time frame |
|---|---|
| blood oxygen saturation;blood pressure;heart rate; | — |
Countries
China
Contacts
The Third Affiliated Hospital of Chongqing Medical University