Skip to content

Clinical study on the relationship between pain during propofol injection under endoscopy and the dose of propofol required to achieve the same depth of sedation

Clinical study on the relationship between pain during propofol injection under endoscopy and the dose of propofol required to achieve the same depth of sedation

Status
Active, not recruiting
Phases
Phase 4
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100172
Enrollment
Unknown
Registered
2025-04-03
Start date
2025-05-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Pain on propofol injection

Interventions

POPI VS no-POPI:no

Sponsors

The Third Affiliated Hospital of Chongqing Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged from 18 to 60 years old; 2. Routine acceptance of upper gastrointestinal endoscopy; 3. ASA grade: Grade I or Grade II; 4. Body mass index is greater than 18 kg/m^2 and less than 28 kg / m^2 (obesity); 5. The intravenous injection site is the back of the hand or the forearm (the size and site of the indwelling needle) 6. Voluntary signing of the informed consent form for anesthesia.

Exclusion criteria

Exclusion criteria: 1. Patients with a contraindication for conventional endoscopic procedures or for refusing anesthesia. 2. Life-threatening circulation, respiratory diseases, active massive bleeding with shock, etc., where the condition is not properly controlled. 3. Liver dysfunction (Child-Pugh C or above), gastrointestinal obstruction, cold fever, bronchial asthma, severe neurological diseases in the past month, etc. 4. Anxiety / depression; 5. Having a history of drug use or such alcohol abuse; 6. The evaluation of patients with a clear difficult airway, patients with morbid obesity and confirmed obstructive sleep apnea can not complete the painless gastroscopy in the outpatient clinic. 7. Unaccompanied people. 8. Patients with allergy or contraindications to propofol; 9. Pregnant women.

Design outcomes

Primary

MeasureTime frame
Pain on propofol injection;Total dose of propofol;

Secondary

MeasureTime frame
blood oxygen saturation;blood pressure;heart rate;

Countries

China

Contacts

Public ContactZhan Li

The Third Affiliated Hospital of Chongqing Medical University

798047503@qq.com+86 133 5034 9211

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026