High blood pressure
Conditions
Interventions
The RDN treatment group:Undergo sympathetic ablation of renal arteries
Control group:Treatment was carried out according to the original treatment protocol without any intervention.
Sponsors
Central Hospital of Putuo District, Shanghai
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Age 18-80 years old; 2. Systolic blood pressure >=140 and =90mmHg and =7mmol/L or glycosylated hemoglobin >=6.5% and =3 months (such as oral medication or insulin); 4. Those who voluntarily participate in this study and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Secondary hypertension (such as renal artery stenosis, pheochromocytoma, primary aldosteronism, etc.); 2. Type 1 diabetes mellitus or acute complications of diabetes mellitus (e.g., ketoacidosis, hyperosmolar state); Severe diabetic complications (e.g., end-stage renal disease, proliferative retinopathy, history of amputation); 3. Renal artery stenosis, severe renal insufficiency (eGFR<30 mL/min/1.73m^2) or dialysis-dependent; 4. Acute myocardial infarction, stroke, unstable angina pectoris or revascularization, severe arrhythmia (such as ventricular fibrillation), or heart failure (NYHA class III-IV) within 3 months.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Change in mean systolic blood pressure in ambulatory blood pressure;Decrease from baseline in office blood pressure;Change from baseline in glycosylated hemoglobin (HbA1c).; | — |
Secondary
| Measure | Time frame |
|---|---|
| Fasting blood glucose results;Insulin indicators;C-peptide;Liver and kidney function indicators; | — |
Countries
China
Contacts
Public ContactXiao Rongxue
Central Hospital of Putuo District, Shanghai
Outcome results
None listed