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Effects of tea polyphenols on gastric mucosal lesions and inflammatory responses in patients with chronic atrophic gastritis: a randomized controlled trial study

Effects of tea polyphenols on gastric mucosal lesions and inflammatory responses in patients with chronic atrophic gastritis: a randomized controlled trial study

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100105
Enrollment
Unknown
Registered
2025-04-02
Start date
2025-04-07
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atrophic Gastritis

Interventions

Control group:Control group: placebo + gastric mucosal protector
Experimental group:Experimental group: tea polyphenol tablet + gastric mucosal protector

Sponsors

Beijing Friendship Hospital ,Capital Medical University
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Age 18-70 years old; 2.Patients with chronic atrophic gastritis confirmed by endoscopy and pathology; 3.Those who are not pregnant and do not plan to become pregnant during the trial; 4.Those who can be followed up regularly; 5.Signed informed consent.

Exclusion criteria

Exclusion criteria: 1.Patients with severe heart, liver, kidney and other organ diseases; 2.Patients with malignant tumours; 3.Combined with organic bowel disease such as inflammatory bowel disease and intestinal obstruction; 4.Patients with coeliac disease, chronic pancreatitis, portal hypertension and other digestive diseases; 5.Patients with mental illness;those who are pregnant, lactating, may not take effective contraceptive measures when pregnant, and those who are preparing to conceive; 6.Those who are allergic to tea polyphenols and/or tepredone.

Design outcomes

Primary

MeasureTime frame
The effectiveness of tea polyphenols in repairing gastric mucosal damage in patients with atrophic gastritis after 6 months of treatment.;

Secondary

MeasureTime frame
Symptom improvement;HP infection status and eradication rate;The degree and activity of mucosal inflammation;Long-term efficacy;

Countries

China

Contacts

Public ContactXing Jie

Beijing Friendship Hospital ,Capital Medical University

xingjie0315@126.com+86 10 63139351

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026