systemic lupus erythematosus
Conditions
Interventions
SLE Disease Group:MSC-EVs with enhanced autophagy activation
Sponsors
Yuebei People’s Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1.Systemic lupus erythematosus (SLE) patients who meet the diagnostic criteria and activity indicators recommended by the American College of Rheumatology (ACR) in 2009 for SLE;The patient is in the active phase of SLE (SLEDAI>6). 2.Healthy volunteers: No history of major illnesses, no recent infections or inflammatory diseases. 3.Sign the informed consent form and agree to participate in this study.
Exclusion criteria
Exclusion criteria: 1.Exclusion criteria for patients with systemic lupus erythematosus (SLE): pregnant or lactating women; Patients with infections, allergies, or other serious systemic or autoimmune diseases. 2.Exclusion criteria for healthy volunteers: Pregnant or lactating women.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| T/B cell subpopulation;inflammatory factors:TNF-a?IFN-?? IL-1?IL-4?IL-6?IL-13; | — |
Countries
China
Contacts
Public ContactLiao Shuzhen
Yuebei People’s Hospital
Outcome results
None listed