Liver fibrosis/cirrhosis
Conditions
Interventions
Case group (Liver transplantation and liver resection surgery):None
Control group (Liver transplantation and liver resection surgery):None
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Case group: Patients with liver fibrosis or cirrhosis are scheduled for liver transplantation or liver biopsy.; and having signed an informed consent form for the use of biological samples in research. 2.Control group: Patients undergoing liver transplantation, hepatic hemangioma resection, or living donor hepatectomy; and having signed an informed consent form for the use of biological samples in research.
Exclusion criteria
Exclusion criteria: 1.Case group: Patients with malignant tumors in organs other than the liver; those who refused to participate in this study. 2.Control group: Patients with pregnancy; those with liver fibrosis or a history of interventional procedures/biological therapy; and those who refused to participate in this study.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The expression levels of candidate factors in liver tissue Immunohistochemical analysis;Perioperative related test indicators;The serum samples are used for analyzing the serum content of the candidate factors.;The mRNA expression levels of candidate factors in liver tissue;The protein expression levels of candidate factors in liver tissue;candidate factors in liver tissue ImmunoThe expression levels of fluorescence analysis;Picro-Sirus-Red stainig in liver tissue; | — |
Secondary
| Measure | Time frame |
|---|---|
| The patient's preoperative basic medical history and the treatment situation in this hospital;patient information;Preoperative patient-related diagnoses;Postoperative patient-related conditions; | — |
Countries
China
Contacts
Public ContactYan Xu
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed