Stroke-related pneumonia
Conditions
Interventions
Experimental group:The patients will be placed in 5 positions in the order of 5 positions with usual care and sequential lateral positioning, and each position will be held for 30 minutes.
Control group:The patient will be turned over and given back percussion every 2 hours with usual care and positioning, and reincubated for 2 hours to change direction.
Sponsors
The First Affiliated Hospital of NanChang University
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: (1) Meet the diagnostic criteria for stroke and be confirmed by head CT scan or MRI; (2) meet the latest diagnostic criteria for stroke-related pneumonia; (3) Age >= 18 years old; (4) Body mass index <= 35kg/m^2; (5) invasive mechanical ventilation is required; (6) The patient or family agrees to participate in the study
Exclusion criteria
Exclusion criteria: (1) Mechanical ventilation time= 48 hours (including discharge and clinical death); (2) multi-organ failure; (3) Haemodynamically unstable patients: adequate fluid resuscitation and two vasopressors in the past 6 hours, or a 30% increase in vasopressor dose, but a sustained mean arterial pressure of less than 60mmHg; (4) Exclude contraindications to lateral decubitus ventilation caused by traumatic factors such as pulmonary contusion, lung infection, respiratory failure, multiple fractures or rib fractures that lead to inability to lie on the side, or severe pressure injury on one side, pleural effusion, etc.; (5) Obvious abdominal distention, gastric residual > 400ml; (6) pneumothorax; (7) Increased intracranial pressure.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| PaO2/FiO2 ratio;inflammatory markers; | — |
Secondary
| Measure | Time frame |
|---|---|
| 24-hour airway sputum aspiration;Duration of mechanical ventilation; | — |
Countries
China
Contacts
Public ContactWang dan
The First Affiliated Hospital of NanChang University
Outcome results
None listed