Chronic liver disease
Conditions
Interventions
Large Model-assisted Group:Perioperative fluid therapy assisted by a large model.
Usual Care Group:Conventional Perioperative Fluid Management.
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1.Aged 18 to 80 years;Patients with chronic liver disease in the preoperative period, that is, those whose diagnosis includes viral hepatitis, metabolic liver disease, drug-induced liver injury, autoimmune hepatitis, or other chronic liver conditions with a disease duration of more than six months, or those with unknown disease duration but with imaging or pathological evidence of cirrhotic changes;Patients undergoing elective surgery: American Society of Anesthesiologists (ASA) physical status classification of II to IV; 2.General anesthesia planned, with an anticipated surgical duration exceeding 3 hours and an expected postoperative hospital stay exceeding 5 days.
Exclusion criteria
Exclusion criteria: 1.Exclusion criteria include patients with severe preoperative cardiovascular and cerebrovascular diseases or renal dysfunction; 2.Patients experiencing critical intraoperative events such as cardiac arrest or refractory anaphylactic shock; 3.Patients with compromised mental status, mental disorders, or lack of self-control; 4.Those who refuse to participate or whose family members decline participation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Incidence of postoperative complications graded III or higher according to the Clavien-Dindo classification.; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative hospital stay duration;Liver failure after hepatectomy;Postoperative pulmonary complications;Postoperative acute kidney injury; | — |
Countries
China
Contacts
Public ContactBin Yi
The First Affiliated Hospital of Army Medical University
Outcome results
None listed