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Comparative Study on Cognitive Impairment between Normal Tension Glaucoma and High Tension Glaucoma and Analysis of Related Influencing Factors

Comparative Study on Cognitive Impairment between Normal Tension Glaucoma and High Tension Glaucoma and Analysis of Related Influencing Factors

Status
Active, not recruiting
Phases
Unknown
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500100085
Enrollment
Unknown
Registered
2025-04-02
Start date
2025-04-02
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Normal tension glaucoma

Interventions

NTG group/HTG group:None

Sponsors

Bejing Tongren Hospital, Capital Medical Uniersity
Lead Sponsor

Eligibility

Sex/Gender
All

Inclusion criteria

Inclusion criteria: NTG Group Inclusion Criteria: 1. Meet the International Classification of Diseases (ICD-10) diagnostic criteria for normal intraocular pressure glaucoma. Diagnosis of glaucomatous visual field defect by reliable Humphrey 24-2 visual field examination with thinning of the corresponding optic disc edges, increased vertical cup-to-disc ratio (>=0.6), or asymmetry of both cups and discs (>=0.2). 2. Best corrected visual acuity > 0.7, refractive error =25mmHg; (2) Cup-to-disc ratio >=0.6 or binocular glass-to-disc ratio difference >0.2;(3) RNFL defect; (4) Early visual field defects. 2. Best corrected visual acuity > 0.7, refractive error < = /-6D. 3. gonioscopy, the angle is open. 4. Voluntarily join this study and sign the informed consent form. (Both groups are gender- and age-matched)

Exclusion criteria

Exclusion criteria: 1.Patients with mental illnesses, any psychosomatic diseases that may affect emotional status, abnormal nervous system or dementia symptoms, as well as those suffering from other central nervous system diseases such as frontotemporal dementia, vascular dementia, etc. 2.Patients diagnosed with retinal vein occlusion, diabetic retinopathy, ischemic optic neuropathy, or other conditions that can lead to visual field defects. 3.Patients with acute myocardial infarction, acute stroke, severe heart, liver, or kidney diseases, and those with recent acute infectious diseases. 4.Patients who are unable to cooperate with relevant ophthalmic examinations due to reasons such as distractibility, poor fixation of gaze, etc. 5.Patients who have not obtained and signed the informed consent form.

Design outcomes

Primary

MeasureTime frame
Cognitive function score;Anxiety state score;Depressive state score;Sleep quality score;

Countries

China

Contacts

Public ContactGuoping Qing

Bejing Tongren Hospital, Capital Medical Uniersity

gptsing@126.com+86 10 58265146

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026