Normal tension glaucoma
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: NTG Group Inclusion Criteria: 1. Meet the International Classification of Diseases (ICD-10) diagnostic criteria for normal intraocular pressure glaucoma. Diagnosis of glaucomatous visual field defect by reliable Humphrey 24-2 visual field examination with thinning of the corresponding optic disc edges, increased vertical cup-to-disc ratio (>=0.6), or asymmetry of both cups and discs (>=0.2). 2. Best corrected visual acuity > 0.7, refractive error =25mmHg; (2) Cup-to-disc ratio >=0.6 or binocular glass-to-disc ratio difference >0.2;(3) RNFL defect; (4) Early visual field defects. 2. Best corrected visual acuity > 0.7, refractive error < = /-6D. 3. gonioscopy, the angle is open. 4. Voluntarily join this study and sign the informed consent form. (Both groups are gender- and age-matched)
Exclusion criteria
Exclusion criteria: 1.Patients with mental illnesses, any psychosomatic diseases that may affect emotional status, abnormal nervous system or dementia symptoms, as well as those suffering from other central nervous system diseases such as frontotemporal dementia, vascular dementia, etc. 2.Patients diagnosed with retinal vein occlusion, diabetic retinopathy, ischemic optic neuropathy, or other conditions that can lead to visual field defects. 3.Patients with acute myocardial infarction, acute stroke, severe heart, liver, or kidney diseases, and those with recent acute infectious diseases. 4.Patients who are unable to cooperate with relevant ophthalmic examinations due to reasons such as distractibility, poor fixation of gaze, etc. 5.Patients who have not obtained and signed the informed consent form.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cognitive function score;Anxiety state score;Depressive state score;Sleep quality score; | — |
Countries
China
Contacts
Bejing Tongren Hospital, Capital Medical Uniersity