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Mechanism of mannose promoting cholesterol excretion

Mechanism of mannose promoting cholesterol excretion

Status
Active, not recruiting
Phases
Early Phase 1
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100084
Enrollment
Unknown
Registered
2025-04-02
Start date
2025-04-07
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Atherosclerosis

Interventions

Group A:Phase I: the volunteers' diet strictly followed the dietary guidelines for Chinese residents (2022). Dietary energy sources accounted for 60% of carbohydrate, 25% of fat, and 15% of protein. T
Group B:The first stage: Based on group a recipes, add cola, fried chicken or other meat dishes. There is no restriction on the intake of additional food and beverages, but it needs to be reported to

Sponsors

Longyan First Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 30 Years

Inclusion criteria

Inclusion criteria: 1) Healthy adults aged 18-30 years, body mass index (BMI) 22-24; 2) Those who can strictly control their daily diet and take mannose on time according to the research protocol; 3) The patients were enrolled after examination by clinicians.

Exclusion criteria

Exclusion criteria: 1) Have underlying disease or family genetic history; 2) Those who do not agree to sign informed consent; 3) Those whose physical conditions are not allowed by the doctor.

Design outcomes

Primary

MeasureTime frame
Cholesterol;Mannose;Blood routine test;Biochemical complete set;Coagulation function and thromboelastography;

Secondary

MeasureTime frame
Routine urine test;Glycated serum protein;Weight;

Countries

China

Contacts

Public ContactSisi Xie

Longyan First Hospital

18111010026@fudan.edu.cn+86 185 5930 5640

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026