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A Clinical Research of Ultrasound-guided Bilateral Costal Margin Block for Postoperative Analgesia After Laparoscopic Cholecystectomy

A Clinical Research of Ultrasound-guided Bilateral Costal Margin Block for Postoperative Analgesia After Laparoscopic Cholecystectomy

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100061
Enrollment
Unknown
Registered
2025-04-02
Start date
2024-04-29
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative analgesia

Interventions

Costal margin block combined with general anesthesia group (CMB group):Ultrasound-guided costal margin block (50 mL of 0.375% ropivacaine and 25 mL on one side)
General anesthesia alone group (Group C):Ultrasound-guided costal margin block (drug is 50 ml of normal saline, 25 ml on one side)

Sponsors

Taizhou Central Hospital (Taizhou University Affiliated Hospital)
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. No history of upper abdominal surgery; 2. Age 18-75 years old; 3. No history of motion sickness, nausea and vomiting and chronic pain; 4. American Society of Anesthesiologists grading ASA Class I-II.

Exclusion criteria

Exclusion criteria: 1. Refusal to sign informed consent; 2. Those who have contraindications to regional block techniques (allergy to local anesthetics, infection around the puncture site and coagulation disorders); 3. American Society of Anesthesiologists grading ASA Class IV-V; 4. The surgical incision is significantly beyond the upper abdominal range; 5. Any cardiovascular and cerebrovascular accidents, such as stroke, myocardial infarction, etc., within 3 months: 6. Patients with dementia or severe cognitive impairment; 7. BMI index > 35.

Design outcomes

Primary

MeasureTime frame
Range of hypoesthesia in the abdomen after block;

Secondary

MeasureTime frame
Numerical rating scale, NRS;Postoperative analgesic use;Intraoperative analgesic use;Analgesic satisfaction score at 24 hours after surgery;Incidence of postoperative nausea and vomiting;

Countries

China

Contacts

Public ContactJiaoyang Jiang

Taizhou Central Hospital (Taizhou University Affiliated Hospital)

736931456@qq.com+86 182 5760 9596

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026