For patients with lumbar spinal stenosis, lumbar disc herniation, lumbar spondylolisthesis and other diseases, we planned to undergo open posterior spinal surgery within two vertebral segments for the first time.
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1.Patients of both sexes, aged 18-70 yr, with BMI of 18-30 kg/m^2, scheduled for the first open posterior lumbar surgery with two or less vertebral segments due to lumbar spinal stenosis, lumbar disc herniation, lumbar spondylolisthesis and other diseases, were enrolled. ASA grade I-III;
Exclusion criteria
Exclusion criteria: 1.Patients with severe cardiopulmonary disease, infection at the puncture site, coagulopathy, allergy to the designed drugs, intraoperative blood loss greater than 500ml, previous history of opioid abuse, history of mental illness or psychotropic drugs, central nervous system disease, and inability to communicate normally.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| VAS score 1h after surgery;VAS score 6h after surgery;VAS score 12h after surgery;15-item recovery quality score 3 days after surgery;VAS score 24h after surgery;VAS score 48h after surgery;VAS score 72h after surgery;15-item recovery quality score 1 day before surgery;15-item recovery quality score 1 day after surgery;15-item recovery quality score 2 days after surgery; | — |
Secondary
| Measure | Time frame |
|---|---|
| Extubation time;SAS score;Time to first rescue analgesia;postoperative nausea and vomiting;respiratory depression; | — |
Countries
China
Contacts
Jingzhou Central Hospital