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Efficacy of Ultrasound-Guided Erector Spinae Plane Block with Liposomal Bupivacaine on Postoperative Analgesia and Recovery Quality in Patients Undergoing Spinal Surgery

Efficacy of Ultrasound-Guided Erector Spinae Plane Block with Liposomal Bupivacaine on Postoperative Analgesia and Recovery Quality in Patients Undergoing Spinal Surgery

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500100055
Enrollment
Unknown
Registered
2025-04-02
Start date
2025-04-20
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

For patients with lumbar spinal stenosis, lumbar disc herniation, lumbar spondylolisthesis and other diseases, we planned to undergo open posterior spinal surgery within two vertebral segments for the first time.

Interventions

R group:Ultrasound-guided erector spinae plane block
LB group:Ultrasound-guided erector spinae plane block

Sponsors

Jingzhou Central Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 70 Years

Inclusion criteria

Inclusion criteria: 1.Patients of both sexes, aged 18-70 yr, with BMI of 18-30 kg/m^2, scheduled for the first open posterior lumbar surgery with two or less vertebral segments due to lumbar spinal stenosis, lumbar disc herniation, lumbar spondylolisthesis and other diseases, were enrolled. ASA grade I-III;

Exclusion criteria

Exclusion criteria: 1.Patients with severe cardiopulmonary disease, infection at the puncture site, coagulopathy, allergy to the designed drugs, intraoperative blood loss greater than 500ml, previous history of opioid abuse, history of mental illness or psychotropic drugs, central nervous system disease, and inability to communicate normally.

Design outcomes

Primary

MeasureTime frame
VAS score 1h after surgery;VAS score 6h after surgery;VAS score 12h after surgery;15-item recovery quality score 3 days after surgery;VAS score 24h after surgery;VAS score 48h after surgery;VAS score 72h after surgery;15-item recovery quality score 1 day before surgery;15-item recovery quality score 1 day after surgery;15-item recovery quality score 2 days after surgery;

Secondary

MeasureTime frame
Extubation time;SAS score;Time to first rescue analgesia;postoperative nausea and vomiting;respiratory depression;

Countries

China

Contacts

Public ContactWang Weilian

Jingzhou Central Hospital

wangweilian27@163.com+86 181 0716 8494

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Jun 11, 2026