Lymphoma, multiple myeloma
Conditions
Interventions
G-CSF monotherapy group:G-CSF mobilization regimen
Combination of G-CSF and IL-11 group:Combined of G-CSF and IL-11 mobilization regimen
Sponsors
East China Hospital Affiliated to Fudan University
Eligibility
Sex/Gender
All
Age
No minimum to 70 Years
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with lymphoma and multiple myeloma, who are indicated for autologous hematopoietic stem cell transplantation. 2.For lymphoma patients who are eligible for transplantation and have achieved complete remission (CR) or partial remission (PR), hematopoietic stem cell transplantation will be performed. 3.For multiple myeloma, patients with CRAB or SLiM symptoms need treatment. Those <=70 years old, with good performance status and physical condition for autografting are preferred. 4.Sign the informed consent form;
Exclusion criteria
Exclusion criteria: 1.Patients who are intolerant to autologous hematopoietic stem cell transplantation; 2.The patient has participated in other clinical trials within 30 days prior to mobilization therapy. 3.The patient has received other treatment regimens during the assessment period. 4.Patients who have used other drugs with stem cell mobilization capabilities. 5.Pregnant or lactating patients; 6.Patients with severe diseases of the cardiovascular system, endocrine system, digestive system, and other major systems. 7.Psychiatric patient; 8.Patients with missing or incomplete important clinical medical record information;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Hematopoietic reconstitution time;Security; | — |
Secondary
| Measure | Time frame |
|---|---|
| Progression-Free Survival;Overall Survival; | — |
Countries
China
Contacts
Public ContactJiexian Ma
East China Hospital Affiliated to Fudan University
Outcome results
None listed