Intracranial atherosclerotic disease
Conditions
Interventions
Observation group:None
Sponsors
The First Affiliated Hospital of Army Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Eligible patients aged between 18 and 80, regardless of gender; 2. Patients diagnosed with severe intracranial atherosclerotic stenosis (stenosis degree 70%-99%) confirmed by CTA, MRA, or intraoperative DSA; 3. Presence of three or more atherosclerotic risk factors; 4. Informed consent form signed; 5. Patients who have not undergone endovascular interventional therapy.
Exclusion criteria
Exclusion criteria: 1. History of intracerebral hemorrhage; 2. Intracranial aneurysm or arterial dissection; 3. Stroke of cardioembolic, small vessel disease (lacunar), other determined etiology, or undetermined etiology (cryptogenic); 4. Patients with large territory cerebral infarction; 5. Intracranial arterial occlusion; 6. Life expectancy <3 months; 7. Contraindications to MRI or critically unstable condition precluding MRI examination; 8. Poor image quality or significant artifacts affecting diagnostic interpretation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Stroke occurrence in the responsible vascular supply area within 1 year; | — |
Secondary
| Measure | Time frame |
|---|---|
| Incidence of ischemic stroke within 1 year;Incidence of hemorrhagic stroke within 1 year;Death events caused by cerebrovascular diseases within 1 year; | — |
Countries
China
Contacts
Public ContactZhenhua Zhou
The First Affiliated Hospital of Army Medical University
Outcome results
None listed