Atopic dermatitis
Conditions
Interventions
Sponsors
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College
Eligibility
Sex/Gender
All
Age
2 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Gender is not limited, the age of the patient >=2 years old; 2. Adult/adolescent patients with atopic dermatitis are diagnosed according to Yao's Chinese diagnostic criteria for atopic dermatitis 3. Those who sign the informed consent form, voluntarily participate in the project and can complete the follow-up as required
Exclusion criteria
Exclusion criteria: 1. Have a malignant tumor or a history of malignant tumor within 5 years before screening; 2. There are other inflammatory skin diseases that may interfere with the evaluation of efficacy (such as psoriasis, parapsoriasis, eosinophilic dermatitis, etc.); 3. Serious diseases of heart, brain, lung, liver, kidney, blood and other important organ systems, which the investigator considers inappropriate to participate in this study; 4. Received immunosuppressant therapy such as systemic glucocorticoids, tripterygium wilfordii, cyclosporine within 4 weeks before the first transplant of the study, or received biological agents (such as dupilumab, omalizumab, etc.) within 3 months; 5. Use of antimicrobial drugs, probiotics/meta preparations, intestinal microecological regulation therapy or other drugs that significantly affect the intestinal flora within 4 weeks; 6. Known active tuberculosis and other active or recurrent serious infections; 7. Those with congenital immunodeficiency or congenital immunodeficiency; 8. Drug abuse, alcoholism, mental abnormalities or poor compliance and inability to cooperate; 9. Women who are trying to get pregnant, pregnant women and lactating women; 10. Investigators who participate in other clinical trials at the same time; 11. Other circumstances that the researcher deems inappropriate to participate
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Serum biomarker;Transcriptome;Microbial sequencing;Microbial metabolite sequencing; | — |
Countries
China
Contacts
Public ContactYao Xu
Hospital for Skin Diseases, Institute of Dermatology, Chinese Academy of Medical Sciences, Peking Union Medical College
Outcome results
None listed