infectious diseases
Conditions
Interventions
Group Precision medicine:None. Input patient basic information into the precision medicine model to predict vancomycin trough concentration
Group Smart Dose:None. Input patient basic information into the Smart Dose model to predict vancomycin trough concentration
Group PrecisePK:None. Input patient basic information into the PrecisePK model to predict vancomycin trough concentration
Sponsors
Nanjing Drum Tower Hospital Group Suqian Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 100 Years
Inclusion criteria
Inclusion criteria: 1 Use injection solution with vancomycin for >= 48 hours; 2 At least one trough concentration monitoring should be conducted during the use of vancomycin
Exclusion criteria
Exclusion criteria: 1 Single dose prophylactic medication during the perioperative period; 2 Local medication; 3 Continuous renal replacement therapy (CRRT) during the use of vancomycin; 4 Hemodialysis patients; 5 Vancomycin trough concentration has not reached steady state; ? The trough concentration exceeds the detection range
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| predictionerror;mean absolute percentage error; | — |
Secondary
| Measure | Time frame |
|---|---|
| mean error;mean absolute error;MAPE% < 30% ; | — |
Countries
China
Contacts
Public ContactWang Jinna
Nanjing Drum Tower Hospital Group Suqian Hospital
Outcome results
None listed