Chronic wound
Conditions
Interventions
Treatment group:Platelet-rich plasma preparation PRP prepared by kit combined with conventional treatment
Control group:Conventional treatment
Sponsors
Shanghai Sixth People's Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: 1) Age >= 18 years and 30 g/L; 7) Hemoglobin (Hgb) >= 100 g/L and platelet count (PLT) >= 100 × 10^9/L; 8) The subject and/or their guardian can understand the purpose of the trial, demonstrate adequate compliance with the trial protocol, and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1) The target wound is expected to require skin grafting or flap repair; 2) dry gangrene caused by vascular disease; 3) Patients with bleeding disorders (such as hemophilia, vitamin K deficiency, etc.), disorders with platelet dysfunction (such as giant platelet syndrome, thrombocytopathia, storage pool disease, thrombocytopathia syndrome, etc.), or other blood-related diseases that researchers have judged unsuitable for platelet-rich plasma collection; 4) Patients with severe heart, liver, lung, renal failure, severe neurological disease, severe cardiovascular disease, malignant tumor, systemic infection or uncontrolled local infection (including target wound), sepsis; 5) History of systemic glucocorticoid therapy within 14 days before or during the screening period; 6) History of target wound glucocorticoid injection within 28 days before or during the screening period; 7) Pregnant or lactating women; 8) Have participated in or are participating in other interventional clinical trials within 28 days prior to screening; 9)The investigator believes that they should not be involved in other situations in this clinical trial.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Bates-Jensen wound score 21 days after initial treatment; | — |
Secondary
| Measure | Time frame |
|---|---|
| Wound healing efficiency;Relative rate of wound healing;Visual Analogue Pain Score (VAS score);Product performance evaluation; | — |
Countries
China
Contacts
Public ContactYuan Ting
Shanghai Sixth People's Hospital
Outcome results
None listed