Knee Osteoarthritis
Conditions
Interventions
Sponsors
Eligibility
Inclusion criteria
Inclusion criteria: 1. patients who met the diagnostic criteria for knee osteoarthritis; 2. Age 45-75 years old, both sexes; 3. In accordance with Kellgren-Lawrence grading standard: grade 3 or below, namely early and middle stage patients; 4. those who accepted the treatment designed for this study and signed the informed consent form; 5. Patients who did not take any other anti-inflammatory analgesics or intra-articular injection therapy in the past 1 month, such as oral NSAIDs analgesics or cartilage protective agents, chondroitin sulfate, glucosamine sulfate (hydrochloride), diaceriin, etc., such as patients who received intra-articular glucocorticoid or sodium hyaluronate injection; 6. not receiving other related treatment within 1 month; 7. good compliance and willing to cooperate with long-term follow-up; 8. clear consciousness, language communication ability and no cognitive impairment; 9. For patients with bilateral KOA, the severe side was used as the standard. If the more severe side did not meet the inclusion criteria, the less severe side was used as the standard.
Exclusion criteria
Exclusion criteria: 1. those who could not accept the study regimen; 2. patients with knee tuberculosis, knee tumor, fracture and other knee trauma, infectious diseases, skin diseases such as severe skin ulcers, defects, or rheumatic diseases; 3. patients with peripheral nerve and vascular injury, ligament rupture; 4. patients with knee osteoarthritis who had undergone total knee arthroplasty; 5. Failure to complete the planned treatment or follow-up plan; 6. women who are pregnant or preparing to become pregnant or breastfeeding.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The Western Ontario and McMaster Universities osteoarthritis index;visual analog pain scores;Infrared thermography map temperature; | — |
Countries
China
Contacts
The No.1 people's Hosipital of Chenzhou