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Diagnostic efficiency of 64Cu/68Ga-TRD2206 PET/CT in patients with urothelial carcinoma and cervical cancer

Diagnostic efficiency of 64Cu/68Ga-TRD2206 PET/CT in patients with urothelial carcinoma and cervical cancer

Status
Recruiting
Phases
Early Phase 1
Study type
Observational
Source
ChiCTR
Registry ID
ChiCTR2500099991
Enrollment
Unknown
Registered
2025-04-01
Start date
2024-10-30
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

urothelium carcinoma and cervical cancer

Interventions

Sponsors

First Medical Center, PLA General Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 79 Years

Inclusion criteria

Inclusion criteria: Subjects who met all the following criteria can be included in this study : 1. Informed consent must be obtained before participating in the study ; 2, 18 years old = 1.5 × 10 ^ 9 / L, platelet count > = 90 × 10 ^ 9 / L, hemoglobin > = 90 g / L ; liver : total bilirubin ( TBIL ) < = 1.5 times upper limit of normal ( ULN ), alanine aminotransferase ( ALT ) and aspartate aminotransferase ( AST ) < = 3.0 × ULN ; kidney : serum creatinine ( SCr ) < = 1.5 × ULN.

Exclusion criteria

Exclusion criteria: Subjects who meet the following exclusion criteria are not permitted to enter this study : 1. Patients or researchers who are unable to accept PET examination due to weight, claustrophobia, radiation phobia, inability to lie for a long time during the examination, etc., determine that the patient has any situation that cannot cooperate with the imaging examination and operation ; 2, 4 weeks received previous chemotherapy, radiotherapy, targeted therapy or other anti-tumor therapy ( except anti-cancer Chinese medicine treatment ) ; 3.Patients with central nervous system ( CNS ) metastasis who have symptoms or are receiving glucocorticoid therapy ; 4.Patients with a history of other malignant tumors ( except for patients who had undergone radical treatment and had been treated for more than 3 years before enrollment and had no evidence of recurrence / metastasis ) ; 5. Complicated with serious or poorly controlled medical diseases, including, but not limited to, uncontrollable infections, hypertension, acute coronary syndrome, or other diseases that researchers believe may affect the study ; 6. Those who are allergic to the study of drugs and their components ; 7.In the 7 days before the study drug injection, the female blood pregnancy test was positive ; 8.Patients who did not agree to take effective contraceptive measures or restrictive behaviors during the study period and 4 weeks after administration ; 9. Lactating women ; 10.There are other conditions that researchers believe are not suitable for the experiment.

Design outcomes

Primary

MeasureTime frame
Maximum Standard Uptake Value,SUV max;

Secondary

MeasureTime frame
Sensitivity, SE;Specificity, SP;Positive predicative value, PPV;

Countries

China

Contacts

Public ContactJinming Zhang

First Medical Center, PLA General Hospital

zhangjm301@163.com+86 138 0121 0291

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026