diabetes
Conditions
Interventions
experimental group:After extubation, the experimental group decided whether to administer the drug according to the hemodynamic parameters immediately after extubation, and all patients with hypertens
control group:After extubation, the experimental group decided whether to administer the drug according to the hemodynamic parameters immediately after extubation, and all patients with hypertension a
Sponsors
Medical ethics committee of of Shaw Hospital, Nanjing Medical University
Eligibility
Sex/Gender
All
Age
18 Years to 65 Years
Inclusion criteria
Inclusion criteria: 1. Gastrointestinal tumor surgery; 2. Diabetes mellitus (medical history> = 5 years, oral hypoglycemic drugs or insulin injection); 3. ASA classification: II~III; 4. Age: 18~64 years old; 5BMI:18~27.9 kg/m².
Exclusion criteria
Exclusion criteria: 1. Unable to complete FMD test; 2. Difficult airway; 3. Intraoperative hemorrhage (loss of >=50% circulating blood volume within 3 h); 4. Intraoperative hemodynamic instability, use of vasoactive drugs >=3 times; 5. Baseline MAP <70 mmHg; 6. Difficulty in extubation or re-intubation after surgery; 7. Admitted to ICU after surgery; 8. Persistent hypotension after admission to PACU; 9. Patients with normal blood pressure immediately after extubation.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Nitroglycerin dosage; | — |
Secondary
| Measure | Time frame |
|---|---|
| Flow-mediated vasodilation parameters (FMD);Nitroglycerin-mediated vasodilation parameters (NID);systolic blood pressure;Diastolic blood pressure;Mean arterial pressure;Pulse oximetry;heart rate;Extubation quality score;Cardiovascular adverse events; | — |
Countries
China
Contacts
Public ContactXiaoyu Liu
Medical ethics committee of of Shaw Hospital, Nanjing Medical University
Outcome results
None listed