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Comparison of 27-gauge dual blade-tip and 25-gauge flat-tip microincision vitrectomy surgery in the treatment of rhegmatogenous retinal detachment

Comparison of 27-gauge dual blade-tip and 25-gauge flat-tip microincision vitrectomy surgery in the treatment of rhegmatogenous retinal detachment

Status
Active, not recruiting
Phases
Phase 4
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099960
Enrollment
Unknown
Registered
2025-04-01
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-04-07

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Primary rhegmatogenous retinal detachment

Interventions

Group B:27-gauge with 20,000cuts per minute pars plana vitrectomy
Group A:25-gauge pars plana vitrectomy

Sponsors

Tianjin Medical University Eye Hospital
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to No maximum

Inclusion criteria

Inclusion criteria: 1. Age>=18 years with capable of signing informed consent; 2. Rhegmatogenous retinal detachment with one or more retinal breaks; 3. Patients who intend to undergo vitrectomy and have surgical indications; 4. Patients who accepted to follow for 3 months or longer after surgery; 5. At least part of the cornea is clear (or the central cornea is clear) to ensure fundus examination, visual function examination, and OCT examination after vitrectomy;

Exclusion criteria

Exclusion criteria: 1. proliferative vitreoretinopathy (PVR) of grade C or greater; 2. Pathological myopia macular hole retinal detachment; 3. Keratopathy affecting the visual field, such as corneal opacity or scarring; 4. A history of any previous vitreoretinal surgical procedures; 5. Incapable of postoperative posturin; 6. Significant ocular comorbidities such as uveitis, uncontrolled glaucoma, and severe or proliferative diabetic retinopathy. 7. External eye infection; 8. A follow-up period of less than 3 months; 9. Uncontrolled systemic or ocular disease;

Design outcomes

Primary

MeasureTime frame
the duration of vitrectomy;

Secondary

MeasureTime frame
the incidence of surgical procedure-related complications.;IOP;best corrected visual acuity;the duration of core vitrectomy;The number of scleral incisions requiring suture after surgery;Retinal reposition rate;Vitrectomy rate of retinal detachment area;

Countries

China

Contacts

Public ContactXiaorong Li

Tianjin Medical University Eye Hospital

xiaorli@163.com+86 22 86428725

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026