neonatal necrotizing enterocolitis
Conditions
Interventions
NEC Grading:none
Sponsors
Sichuan Provincial Maternity and Child Health Care Hospital
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1. 28 weeks <= gestational age <32 weeks or 1000g<= weight <=1500g; 2. no history of asphyxia rescue at birth; 3. no history of sedative or analgesic medication applied prior to the cerebral function test; 4. complete clinical data.
Exclusion criteria
Exclusion criteria: 1. Confirmed diagnosis of neonatal hypoxic-ischemic encephalopathy, congenital inherited metabolic disorders, severe congenital malformations, and neonatal hyperbilirubinemic encephalopathy; 2. Confirmed diagnosis of grade III or IV intraventricular hemorrhage, periventricular white matter softening, and central nervous system infection prior to NEC; 3. Those who did not complete the relevant examinations in the appropriate window period.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| The proportion and degree of brain injury;Amplitude-integrated EEG; | — |
Secondary
| Measure | Time frame |
|---|---|
| Neonatal Behavioral Neurological Assessment; head circumference;Cranial ultrasound;Fundus screening;Hearing screening;Number of days in hospital;survival rate;syndrome; | — |
Countries
China
Contacts
Public ContactZhou Jun
Sichuan Provincial Maternal and Child Health Hospital
Outcome results
None listed