patient-controlled analgesia
Conditions
Interventions
Test group 1:Osalidine is prepared at a concentration of 0.5 mg/kg and diluted with normal saline to a total volume of 100 ml. The loading dose is 1 mg, the background dose is 2 ml/h, the additional d
Test group 2:Osalidine is prepared at a concentration of 0.5 mg/kg and diluted with normal saline to a total volume of 100 ml. The loading dose is 1.5 mg, the background dose is 2 ml/h, the additional
Control group :Sufentanil 2 mcg/kg, diluted with normal saline to 100 ml. The loading dose is 10 mcg, the background dose is 2 ml/h, and the additional dose is 2 ml each time. The lockout time is 15 m
Sponsors
Huazhong University Of Science And Technology Union Shenzhen Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 70 Years
Inclusion criteria
Inclusion criteria: 1. Patients scheduled for thoracoscopic segmentectomy of the lung; 2. Age:18-65 years old; 3. ASA grade I - III.
Exclusion criteria
Exclusion criteria: 1. History of severe underlying heart and lung diseases; 2. Severe liver and kidney dysfunction; 3. History of allergy to anesthetic drugs and local anesthetics; 4. History of severe mental illness; 5. Thoracic and thoracic cage deformity; 6. Coagulation dysfunction; 7. Local infection at puncture site; 8. Long-term use of analgesic drugs; 9. Previous history of lung surgery; 10. Unable to communicate normally; 11. Conversion to thoracotomy for the patient; 12. Transfer to intensive care unit after surgery; 13. The surgery time exceeds 3 hours.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Visual Analogue Scale; | — |
Secondary
| Measure | Time frame |
|---|---|
| The initial pressing time for the first administration of patient-controlled intravenous analgesia;Number of times of pressing for patient-controlled intravenous analgesia;The time and dosage of the first postoperative remedial analgesia administration;Total dosage of drugs studied within 48 hours;IL-1a;IL-6C;IL-10;CRP; | — |
Countries
China
Contacts
Public ContactFeng Guangju
Huazhong University Of Science And Technology Union Shenzhen Hospital
Outcome results
None listed