Acute Kidney Injury after Cardiac Surgery with Cardiopulmonary Bypass
Conditions
Interventions
NAKI Group:None
Sponsors
Luoyang Central Hospital
Eligibility
Sex/Gender
All
Age
18 Years to No maximum
Inclusion criteria
Inclusion criteria: 1. Age> 18 years old; 2. Planned CPB cardiac surgery; 3. Ejection fraction >=35%, cardiac function grade II.-IV., no myocardial infarction in the past 1 month; 4. No previous history of cardiac surgery; 5. No electrolyte or acid-base balance disorders were found; 6. No history of infectious or allergic diseases; 7. Gender is not limited, patients and their families are willing to participate in this experiment and sign the informed consent form.
Exclusion criteria
Exclusion criteria: 1. Patients with CKD and chronic dialysis before surgery; 2. AKI has occurred before surgery (Scr increased by more than 26.5 umol/L or 50% from the baseline value); 3. Combined with renal tumors, kidney stones, urinary tract obstruction, chronic liver disease, liver cirrhosis; 4. History of septic shock, infection, and autoimmune diseases; 5. Patients who have suffered cardiac arrest within 48 hours of surgery or died in cardiac arrest; 6. Patients who need intra-aortic balloon counterpulsation after surgery; 7. Patients who need to have surgery on other parts at the same time; 8. Patients with incomplete clinical data.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Neutrophil gelatinase-associated lipocalin;Soluble urokinase-type plasminogen activator receptor;Matrix metalloproteinase 7;Serum creatinine; | — |
Secondary
| Measure | Time frame |
|---|---|
| Surgical time;CPB time;Intraoperative urine output; | — |
Countries
China
Contacts
Public ContactXu Xuanxuan
Luoyang Central Hospital
Outcome results
None listed