Common bile duct stones
Conditions
Interventions
Group A:Slow balloon dilation + ENBD
Group B:Duodenal papillotomy balloon dilation ENBD
Sponsors
The First Affiliated Hospital,Sun Yat-sen University
Eligibility
Sex/Gender
All
Age
18 Years to 80 Years
Inclusion criteria
Inclusion criteria: 1. Imaging examination showed that the maximum diameter was less than 1.0cm, and the diameter of the common bile duct was =100×10^9/L Serum creatinine < = 1.5 × ULN INR < 1.5, or prothrombin time < ULN 4 seconds; 6. The patient has good compliance, can cooperate with the trial observation, and sign a written informed consent form.
Exclusion criteria
Exclusion criteria: 1. Acute obstructive purulent cholangitis; 2. Preoperative complication with acute pancreatitis; 3. Malignant tumors of the bile ducts; 4. After gastrectomy; 5. Previous ERCP; 6. Imaging showed intrahepatic bile duct stones; 7. Patients with obvious stenosis of intrahepatic and extrahepatic bile ducts, or combined with immune or sclerosing cholangitis; 8. HCG-positive females of childbearing potential or lactating females; 9. Poor general condition or cachexia; 10. Any of the following conditions within the 12 months prior to the start of the study: myocardial infarction, severe/unstable angina, coronary artery bypass grafting, congestive heart failure, cerebrovascular accident (including transient ischemic attack), pulmonary embolism; Occurring: Arrhythmias according to NCI-CTCAE criteria >=grade 2 with QTc interval prolongation (>450 msec for males and 470 msec > females); 11. History of malignancy within 5 years; 12. Renal insufficiency, requiring peritoneal dialysis or hemodialysis; 13. Severe dysfunction of other important organs; 14. Hemophilia or bleeding tendency, taking therapeutic amounts of coumarin derivatives and other anticoagulant therapy; 15. History of previous organ transplantation; 16. Known HIV infection; 17. Have a mental illness; 18. Refuse to participate; 19. Patients with other serious acute or chronic physical or psychiatric diseases or abnormal laboratory tests that may increase the risk associated with participating in study treatment, or that may interfere with the interpretation of study results or that the investigator considers unsuitable for enrollment.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Post-ERCP pancreatitis; | — |
Secondary
| Measure | Time frame |
|---|---|
| Success rate of stone removal;Short-term complications;Long-term complications; | — |
Countries
China
Contacts
Public ContactYunpeng Hua
The First Affiliated Hospital,Sun Yat-sen University
Outcome results
None listed