Nasopharyngeal and skull base radiation-induced osteoradionecrosis
Conditions
Interventions
Osteoradionecrosis Grading:None
Sponsors
The Third Affiliated Hospital Sun Yat-sen University
Eligibility
Sex/Gender
All
Inclusion criteria
Inclusion criteria: 1.Patients diagnosed with radiation-induced nasopharyngeal and skull base tissue necrosis; 2.History of radiotherapy and chemotherapy for nasopharyngeal malignancy; 3.Patient and family understand the risks and efficacy of surgical treatment; 4.General physical condition suitable for surgical treatment after evaluation;
Exclusion criteria
Exclusion criteria: 1.Patients requiring surgery due to recurrence after radiotherapy and chemotherapy for nasopharyngeal cancer; 2.Patients with other malignant tumors besides nasopharyngeal cancer; 3.Postoperative pathology indicating tumor residue or recurrence; 4.Inability to understand surgical treatment risks and efficacy; 5.General condition unable to tolerate general anesthesia and surgical treatment; 6.Patients with psychiatric disorders; 7.Pregnant women and pediatric patients.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Patient survival time;Patient survival status; | — |
Secondary
| Measure | Time frame |
|---|---|
| Re-operation rate;Pain score;Quality of life score;Postoperative tissue/mucosal flap healing classification; | — |
Countries
China
Contacts
Public ContactZhaohui Shi
The Third Affiliated Hospital Sun Yat-sen University
Outcome results
None listed