Each year, approximately 4.5 million people worldwide are disabled by hip fractures, a number expected to rise to 21 million annually over the next 40 years. Hip fractures are a leading cause of disability globally, with healthcare costs in the U.S. projected to reach $9.8 billion by 2040, and $650 million in Canada. As three-quarters of the global population live in Asia, the region is expected t
Conditions
Interventions
Stimulation group:Transcutaneous Auricular Vagus Nerve Stimulation
Sham stimulation group:Sham stimulation group
Sponsors
Xiaoshan Hangzhou Xiaoshan Orthopaedics TCM Hospital
Eligibility
Sex/Gender
All
Age
18 Years to 85 Years
Inclusion criteria
Inclusion criteria: 1.Age between 65 and 85 years; 2.Patients diagnosed with hip fracture who seek treatment at this hospital and are scheduled for hip arthroplasty under general anesthesia; 3. Voluntarily participate in the study and sign the informed consent form; 4.American Society of Anesthesiologists (ASA) physical status classification of 1-3; 5.Able to understand the study process and the use of various assessment scales, and can effectively communicate with the researchers.
Exclusion criteria
Exclusion criteria: 1.Patients with treatable arrhythmias; 2.Patients with neuromuscular diseases or left-sided auricular dermatitis; 3.History of substance abuse, including opioids; 4.Patients unable to cooperate with assessments; 5.Patients who have experienced seizures or recurrent syncope in the past 5 years; 6.History of transient ischemic attack or cerebrovascular accident; 7.Patients who have received vagus nerve stimulation or acupuncture treatment within the last month before the study; 8.Patients currently participating in other clinical trials; 9.Vulnerable populations, including individuals with mental illness, cognitive impairment, critically ill patients, minors, pregnant women, and illiterate individuals.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Cumulative fentanyl consumption over the first 24 hours postoperatively; | — |
Secondary
| Measure | Time frame |
|---|---|
| Postoperative opioid consumption and pain scores.;Postoperative recovery quality;Postoperative sleep quality; | — |
Countries
China
Contacts
Public ContactHan Qiuwan
Xiaoshan Hangzhou Xiaoshan Orthopaedics TCM Hospital
Outcome results
None listed