Bronchopulmonary dysplasia of the newborn
Conditions
Interventions
The IVIG group:Intravenous Immunoglobulin
Sponsors
China Welfare Society International Peace Maternal and Child Health Hospital
Eligibility
Sex/Gender
All
Age
No minimum to 1 Years
Inclusion criteria
Inclusion criteria: 1.Gestational age between 25 weeks and 31 weeks + 6 days; 2.Admission within 24 hours after birth. 3.Clinical symptoms and chest X-ray results show a highly suspicion of BPD.
Exclusion criteria
Exclusion criteria: 1.Major congenital anomalies(e.g., congenital heart disease, congenital craniocerebral deformity, congenital structural abnormality of respiratory system, congenital hereditary metabolic disease); 2.Chromosomal defects (e.g., trisomy 13, 18, 21); 3.Severe intracranial hemorrhage; 4.Multiple organ failure; 5.Infants who received hydrocortisone or other systemic glucocorticoids for at least 14 cumulative days or within 7 days before trial entry; 6.With severe lung infections; 7.Other circumstances that the investigator determines are not suitable for participation in this study;
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Survival without bronchopulmonary dysplasia at 36 weeks of postmenstrual age; | — |
Secondary
| Measure | Time frame |
|---|---|
| Duration of mechanical ventilation;Duration of O2 supplementation;Time to improvement in pulmonary imaging;Time to improvement in lung ultrasound imaging;Preterm birth complications; | — |
Countries
China
Contacts
Public ContactFu Xuemei
China Welfare Society International Peace Maternal and Child Health Hospital
Outcome results
None listed