Septic Shock
Conditions
Interventions
Mon-Septic Group:Using a high-frequency linear array probe (e.g., 7–12 MHz), the lumen diameters (Ds, Dd) and flow parameters (PSV, EDV, etc.) of the bilateral common carotid arteries are measured at
Septic Shock Group:Using a high-frequency linear array probe (e.g., 7–12 MHz), the lumen diameters (Ds, Dd) and flow parameters (PSV, EDV, etc.) of the bilateral common carotid arteries are measured
Sponsors
The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)
Eligibility
Sex/Gender
All
Age
18 Years to 75 Years
Inclusion criteria
Inclusion criteria: Non-septic Group (1) Age >= 18 years; (2) APACHE II score >8 points; (3) No evidence of infection; (4) No obvious evidence of organ dysfunction, primarily consisting of patients undergoing major surgical procedures (e.g., general surgery, orthopedic surgery); (5) Hemodynamically stable without the use of vasoactive agents; (6) Voluntary participation with signed informed consent. Septic Shock Group (1) Age >= 18 years; (2) Meeting the Sepsis-3 diagnostic criteria; (3) Patients in the acute phase of septic shock; (4) Voluntary participation with signed informed consent.
Exclusion criteria
Exclusion criteria: (1) A prior clear diagnosis of significant carotid atherosclerotic plaques (e.g., IMT > 1.2 mm or plaque formation) along with severe condition; (2) Concomitant severe cardiomyopathy, arrhythmia, congenital heart disease, or other conditions that may significantly affect hemodynamics; (3) Concomitant active hepatic or renal failure or other severe systemic diseases (e.g., advanced malignant tumors); (4) Poor ultrasound image quality that precludes reliable speckle tracking analysis; (5) Pregnant or lactating women (as hormonal changes may affect vascular status); (6) Withdrawal from the study or inability to complete follow-up for other reasons.
Design outcomes
Primary
| Measure | Time frame |
|---|---|
| Carotid arterial circumferential strain(CS);Carotid artery elasticity(ß2); | — |
Secondary
| Measure | Time frame |
|---|---|
| Carotid Systolic Diameter(Ds);Carotid Diastolic Diameter;Carotid artery elasticity(ß1);Carotid Systolic Peak Velocity (PSV);Carotid End-Diastolic Velocity (EDV); | — |
Countries
China
Contacts
Public ContactXu Qiancheng
The First Affiliated Hospital of Wannan Medical College (Yijishan Hospital of Wannan Medical College)
Outcome results
None listed