Skip to content

Effect and Mechanism of Transcranial Magnetic Stimulation in Different Modes when Treating Post-stroke Cognitive Impairment

Effect and Mechanism of Transcranial Magnetic Stimulation in Different Modes when Treating Post-stroke Cognitive Impairment

Status
Recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099802
Enrollment
Unknown
Registered
2025-03-28
Start date
2023-11-15
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Cognitive impairment after stroke

Interventions

Treatment group1:Theta burst stimulation
Treatment group2:High frequency stimulation

Sponsors

China Rehabilitation Research Center
Lead Sponsor

Eligibility

Sex/Gender
All
Age
18 Years to 75 Years

Inclusion criteria

Inclusion criteria: 1. First onset or past onset without significant sequelae (pre-stroke modified Rankin Scale score (mRS)=10 points and <27 points); 5. age between 18 and 65 years old (including 18 and 65 years old); 6. understand the trial and sign the informed consent.

Exclusion criteria

Exclusion criteria: 1. Patients with pacemakers, cochlear implants or other metal foreign bodies and any electronic equipment implanted in the body, such as contraindications to TMS treatment; 2. Cognitive dysfunction caused by diseases other than stroke, such as Alzheimer's disease (AD) and acquired brain injury (TBI), which have been clearly diagnosed before stroke; 3. Clinically diagnosed with severe anxiety/depression or affective disorder, taking antidepressants or psychostimulants; 4. severe aphasia, unable to cooperate with the completion of cognitive function assessment; 5. in the acute stage of various systemic diseases, and the condition is life-threatening; 6. Previous brain disease, such as brain tumor, brain trauma, skull defect and epilepsy within 1 month; 7. Other abnormal conditions that the investigator determines do not meet the test conditions, such as pregnancy; 8. is participating in other clinical research trials; 9. Transcranial magnetic stimulation therapy has been performed within the past 1 month.

Design outcomes

Primary

MeasureTime frame
Montreal cognitive assessment scale;

Secondary

MeasureTime frame
Mini-mental state assessment scale;Loewenstein Occupational Therapy Cognitive Assessment;electroencephalography;

Countries

China

Contacts

Public ContactHao Zhang

China Rehabilitation Research Center

979499358@qq.com+86 152 0080 6744

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Feb 4, 2026