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Observational Study on the Application of Esketamine Sulfate for Preventing Postoperative Sore Throat After Laryngeal Mask Airway Ventilation for Gynecological Laparoscopic Surgery

Observational Study on the Application of Esketamine Sulfate for Preventing Postoperative Sore Throat After Laryngeal Mask Airway Ventilation for Gynecological Laparoscopic Surgery

Status
Active, not recruiting
Phases
Unknown
Study type
Interventional
Source
ChiCTR
Registry ID
ChiCTR2500099787
Enrollment
Unknown
Registered
2025-03-28
Start date
2025-04-01
Completion date
Unknown
Last updated
2025-03-31

For informational purposes only — not medical advice. Sourced from public registries and may not reflect the latest updates. Terms

Conditions

Postoperative sore throat

Interventions

25 mg group:25 mg esketamine sulfate gargle before surgery
50 mg group:50 mg esketamine sulfate gargle before surgery

Sponsors

Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)
Lead Sponsor

Eligibility

Sex/Gender
Female
Age
18 Years to 60 Years

Inclusion criteria

Inclusion criteria: 1. Patients aged 18-60 years who underwent gynecological laparoscopic surgery under general anesthesia with laryngeal mask cannula; 2. ASA I-II.

Exclusion criteria

Exclusion criteria: 1. Preoperative chronic throat pain or/and inflammation; 2. Respiratory system diseases, such as bronchitis, bronchitis, COPD, etc.; 3. Allergic to magnesium sulfate or contraindicated; 4. Operation time less than 1 hour or more than 4 hours; 5. Suspicious and expected difficult airway.

Design outcomes

Primary

MeasureTime frame
Postoperative Sore Throat;

Secondary

MeasureTime frame
Hyoxemia;nausea and vomiting;Dysphagia;blood gas analysis;General information (age; Height; Weight; BMI);

Countries

China

Contacts

Public ContactXiangsheng Xiong

Huai'an Hospital Affiliated to Yangzhou University (The Fifth People's Hospital of Huai'an)

158193942@qq.com+86 177 9898 2001

Outcome results

None listed

Source: ChiCTR (via WHO ICTRP) · Data processed: Aug 9, 2026